Santa Ana, CA

Santa Ana Phase II-IV Clinical Pharmacology Unit

Full-service research capabilities in ophthalmology, cosmetology and aesthetics

Santa Ana, CA

Our Santa Ana ophthalmology clinical research center features two clinical pharmacology units (CPUs) and outpatient sites with full-service research capabilities in ophthalmology, cosmetology and aesthetics. The Santa Ana facility offers a network of more than 20 referring ophthalmologists and optometrists throughout Southern California.

Key Features/Capabilities:
  • 10,000+ database of active patients of varying ages and demographics
  • The only Phase I ophthalmology unit in the country
  • Access to 40,000+ patients through our ophthalmology/optometry referral network throughout Southern California
  • Three ophthalmology-trained investigators (2 MDs, 1 OD)
  • Access to a well-established global network of investigators in dry eye disease, dysfunctional tear syndromes, ocular surface reconstruction and other ophthalmologic diseases
 Device Experience:
  • Contact lenses
  • Diagnostic software
  • Diagnostic equipment
Surgical Experience
  • Excimer ocular surgery
  • Phacoemulsification
  • Lens replacement
  • Implants
  • Plug insertion
  • Dermatology/plastic surgery
Studies Performed:
  • Corneal and external diseases
  • First in human (FIH)
  • Uveitis
  • Vitreoretinal diseases
  • Glaucoma
  • Neuro-ophthalmology
  • Oculoplastics
  • Pediatric ophthalmic conditions
  • Computerized visual acuity assessment (ETDRS, contrast sensitivity, glare, ATS
    • Amblyopia treatment study and HACSS-Holladay automated contrast sensitivity system
  • Autorefractor/keratometry
  • Fundus photography (non-mydriatic, mydriatic, fluorescein angiography, indocyanine green angiography)
Optical coherence tomography of the:
  • Iridocorneal angle
  • Cornea
  • Retina-macula
  • Optic nerve
  • Scanning laser polarimetry
  • Confocal scanning laser ophthalmoscope
  • Corneal topography (Scheimpflug/Piaceido slit-scanning)
  • Ultrasound pachymetry-corneal thickness measurement
  • Confocal microscopy
  • Specular microscopy
  • Automated threshold static perimetry of visual fields
  • Goldmann kinetic perimetry
  • Preferential hyperacuity perimetry
  • A-scan ultrasound biometry
  • B-scan ultrasonography of the eye and orbit
  • Electro diagnostics (ERG,EOG, VEP)
  • Multispectral retinal imaging
  • Macular pigment density testing
  • Impression cytology
  • Tear osmolarity testing (laboratory microanalysis of the tear fluid)
  • Color vision assessment (RGB anomaloscope, D-15, FM-100, pseudoisochromatic plates, Farnsworth color vision testing)
Diagnostic Procedure Experience:
  • Corneal staining
  • Endothelial cell count
  • Schirmer’s testing
  • Lissamine green staining
  • Gonioscopy
  • Intraocular pressure measurements
  • Pachymetry
  • Pupillometry
  • Slit lamp assessments
  • Visual field examinations
  • Anterior segment OCT imaging

Investigator Profile

Dr. Michael Sheety

Dr. Michael Sheety is the Medical and Surgery Director of Ophthalmology and Aesthetics at WCCT’s clinical ophthalmology research center.

Board-certified and fellowship trained in all aspects of refractive eye care, including suture-less surgery and corneal transplantation, Dr. Sheety has performed thousands of vision correction procedures and has made presentations all over the U.S. on subjects ranging from laser vision correction to macular degeneration. Additionally, he trains other surgeons in vision correction techniques on a monthly basis, and is consulted by other eye surgeons on complicated cases such as decreased vision, nonhealing ulcers, severe scarring and eye transplantations.

In addition to laser vision correction, Dr. Sheety performs reconstructive and cosmetic eyelid surgery. Dr. Sheety has extensive experience in facial cosmetics and reconstruction from traumatic injuries and burns. Currently, he is the chief consultant at the Children’s Hospital of Orange County for all reconstructive eyelid injuries and the Grossman Burn Center at Western Medical Center, Santa Ana.

Prior to joining WCCT as the Medical and Surgery Director of Ophthalmology and Aesthetics, Dr. Sheety conducted over 50 clinical research trials in the areas of ophthalmology and cosmetology/aesthetics.


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